SS-31 (Elamipretide)

Mitochondrial-targeted peptide. Restores cardiolipin, boosts ATP, and reduces oxidative stress.

Route: SubQShelf life once mixed: ~30 daysCategory: Longevity

What SS-31 (Elamipretide) is

SS-31, also known as Elamipretide, is a small, aromatic-cationic peptide designed to selectively target mitochondria. It primarily localizes to the inner mitochondrial membrane where it interacts with cardiolipin, a unique phospholipid essential for mitochondrial structure and bioenergetics. By binding to cardiolipin, SS-31 helps to stabilize the inner mitochondrial membrane, protect it from oxidative damage, and preserve the integrity of the electron transport chain. This action supports efficient ATP production and reduces the generation of reactive oxygen species. While its plasma half-life is relatively brief, its sustained presence within mitochondria allows for prolonged cellular effects, working to restore mitochondrial function.

Researchers investigating SS-31's potential often observe effects over a period of weeks to months, with cellular improvements potentially preceding observable functional benefits. Its role in mitochondrial support makes it a candidate for exploration alongside other compounds aiming to optimize cellular energy and antioxidant defenses, though specific research in this area is ongoing. Research protocols have varied widely, but typical experimental cycles might range from several weeks to a few months depending on the study’s objectives. Notable considerations include its high selectivity for mitochondria and its capacity to cross biological barriers effectively. It is important to emphasize that SS-31 is strictly for research purposes and is not intended for medical treatment or diagnosis.

Commonly reported effects

Mitochondrial repair
Energy
Cardiovascular support

Reported side effects & considerations

Minimal reported

Storage & handling

LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.

AFTER RECONSTITUTION: refrigerate 2-8°C. Do NOT freeze. Discard after 30 days OR if the solution becomes cloudy, discolored, or contains particulates.

What people track

Because individual responses vary so much, the useful thing is your own record: what you logged and when, how much is left in the vial, and how your chosen metrics move over the weeks. Peptide Wizard keeps all of that in one place, alongside a 3D reference vial for SS-31 (Elamipretide).

FAQ

What is SS-31 (Elamipretide)?

Mitochondrial-targeted peptide. Restores cardiolipin, boosts ATP, and reduces oxidative stress.

What do people commonly report with SS-31 (Elamipretide)?

Commonly reported effects include mitochondrial repair, energy, cardiovascular support.

How should SS-31 (Elamipretide) be stored?

LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.

How do I keep track of SS-31 (Elamipretide) in my research log?

Peptide Wizard lets you record each entry, keep a vial ledger so you know what's left, and chart your own metrics over time. It is a logbook and reference only — it does not calculate or recommend doses.