Melanotan I
Alpha-MSH analog. Slower, milder tanning effect than MT-II with fewer side effects.
What Melanotan I is
Melanotan I, also known as Afamelanotide, is a synthetic analog of alpha-Melanocyte Stimulating Hormone (alpha-MSH), a naturally occurring peptide in the body. It primarily acts as an agonist for the melanocortin 1 receptor (MC1R), which is predominantly found on melanocytes, the cells responsible for producing pigment. By binding to and activating MC1R, Melanotan I stimulates the process of melanogenesis, leading to increased production of melanin, the pigment that determines skin, hair, and eye color. This peptide is designed for sustained action compared to native alpha-MSH, allowing for a more prolonged stimulation of melanin production.
In practical research settings, Melanotan I is observed to induce a gradual tanning effect, typically developing over several weeks of consistent administration. Its slower and milder action, compared to other melanocortin peptides, often results in fewer reported side effects. Researchers typically investigate cycles lasting several weeks to months to achieve the desired level of pigmentation, followed by a potential maintenance phase. It is important to note that Melanotan I is an investigational research compound and is not approved for human medical use, and thus should not be considered for personal use or as a therapeutic agent.
Commonly reported effects
- Gradual skin tanning
- Skin damage reduction
Reported side effects & considerations
- Mild nausea
- Rare facial flushing
Storage & handling
LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.
AFTER RECONSTITUTION: refrigerate 2-8°C. Do NOT freeze. Discard after 30 days OR if the solution becomes cloudy, discolored, or contains particulates.
What people track
Because individual responses vary so much, the useful thing is your own record: what you logged and when, how much is left in the vial, and how your chosen metrics move over the weeks. Peptide Wizard keeps all of that in one place, alongside a 3D reference vial for Melanotan I.
FAQ
What is Melanotan I?
Alpha-MSH analog. Slower, milder tanning effect than MT-II with fewer side effects.
What do people commonly report with Melanotan I?
Commonly reported effects include gradual skin tanning, skin damage reduction.
How should Melanotan I be stored?
LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.
How do I keep track of Melanotan I in my research log?
Peptide Wizard lets you record each entry, keep a vial ledger so you know what's left, and chart your own metrics over time. It is a logbook and reference only — it does not calculate or recommend doses.
More in Aesthetics
Melanotan IISynthetic analog of alpha-MSH. Induces melanogenesis for skin tanning.…This page is educational. It does not contain dosing guidance and is not medical advice.