Ipamorelin

Selective GH secretagogue that stimulates natural growth hormone release without affecting cortisol or prolactin.

Route: SubQShelf life once mixed: ~30 daysCategory: Growth Hormone

What Ipamorelin is

Ipamorelin is a synthetic pentapeptide that functions as a selective growth hormone secretagogue. It acts as an agonist at the growth hormone secretagogue receptor (GHSR-1a), primarily located in the pituitary gland. By binding to these receptors, Ipamorelin stimulates the pituitary to release endogenous growth hormone (GH) in a pulsatile manner, mimicking the body's natural secretion patterns. A notable characteristic is its selectivity, as it promotes GH release without significantly increasing levels of other hormones such as cortisol, prolactin, or adrenocorticotropic hormone (ACTH), which can be a consideration with other GH-releasing compounds. Its mechanism aims to enhance the body's natural GH production.

In research settings, observed effects from Ipamorelin administration are generally not immediate and typically become apparent over a period of several weeks to months. It is often investigated alongside growth hormone-releasing hormone (GHRH) analogues, such as CJC-1295 (with DAC), to create a more sustained and amplified release of growth hormone pulses. Research protocols commonly involve administration cycles ranging from 8 to 12 weeks, though duration can vary based on specific study objectives. A key consideration for researchers is its targeted action on GH release with minimal impact on other key hormonal pathways. Ipamorelin is a research chemical and is not approved for human medical use.

Commonly reported effects

Improved sleep quality
Lean muscle gain
Fat loss
Better recovery

Reported side effects & considerations

Mild head flush
Temporary hunger increase

Storage & handling

LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.

AFTER RECONSTITUTION: refrigerate 2-8°C. Do NOT freeze. Discard after 30 days OR if the solution becomes cloudy, discolored, or contains particulates.

What people track

Because individual responses vary so much, the useful thing is your own record: what you logged and when, how much is left in the vial, and how your chosen metrics move over the weeks. Peptide Wizard keeps all of that in one place, alongside a 3D reference vial for Ipamorelin.

FAQ

What is Ipamorelin?

Selective GH secretagogue that stimulates natural growth hormone release without affecting cortisol or prolactin.

What do people commonly report with Ipamorelin?

Commonly reported effects include improved sleep quality, lean muscle gain, fat loss, better recovery.

How should Ipamorelin be stored?

LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.

How do I keep track of Ipamorelin in my research log?

Peptide Wizard lets you record each entry, keep a vial ledger so you know what's left, and chart your own metrics over time. It is a logbook and reference only — it does not calculate or recommend doses.