
5-Amino-1MQ
Selective NNMT enzyme inhibitor. Reallocates methyl donors to preserve lean mass while promoting fat loss.
What 5-Amino-1MQ is
5-Amino-1MQ operates as a selective, small molecule inhibitor of the nicotinamide N-methyltransferase (NNMT) enzyme. The NNMT enzyme plays a role in cellular metabolism by methylating nicotinamide, thereby depleting S-adenosylmethionine (SAM) levels, which are critical universal methyl donors. By inhibiting NNMT, 5-Amino-1MQ aims to prevent this depletion, consequently increasing the intracellular availability of SAM. This increase in SAM levels is proposed to reallocate methyl donors for various metabolic pathways, potentially influencing cellular energy expenditure, fat oxidation, and the preservation of lean tissue. Specific pharmacokinetic data, including a precise human half-life, is still under investigation for this research compound.
The observed effects, such as a shift towards fat utilization and maintenance of lean mass, are generally gradual and may become apparent over periods of multiple weeks. While specific synergistic combinations are still under investigation, researchers may explore its use alongside other compounds targeting metabolic pathways or body composition. It is crucial to remember that 5-Amino-1MQ is strictly for research purposes and is not approved for human therapeutic use or consumption.
Commonly reported effects
- Preserves lean mass
- Enhances fat oxidation
- Metabolic flexibility
- Anti-obesity
Reported side effects & considerations
- Mild GI upset
- Rare headache
Storage & handling
LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.
AFTER RECONSTITUTION: refrigerate 2-8°C. Do NOT freeze. Discard after 30 days OR if the solution becomes cloudy, discolored, or contains particulates.
What people track
Because individual responses vary so much, the useful thing is your own record: what you logged and when, how much is left in the vial, and how your chosen metrics move over the weeks. Peptide Wizard keeps all of that in one place, alongside a 3D reference vial for 5-Amino-1MQ.
FAQ
What is 5-Amino-1MQ?
Selective NNMT enzyme inhibitor. Reallocates methyl donors to preserve lean mass while promoting fat loss.
What do people commonly report with 5-Amino-1MQ?
Commonly reported effects include preserves lean mass, enhances fat oxidation, metabolic flexibility, anti-obesity.
How should 5-Amino-1MQ be stored?
LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.
How do I keep track of 5-Amino-1MQ in my research log?
Peptide Wizard lets you record each entry, keep a vial ledger so you know what's left, and chart your own metrics over time. It is a logbook and reference only — it does not calculate or recommend doses.
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This page is educational. It does not contain dosing guidance and is not medical advice.