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MK-677 shelf life: how long it lasts once mixed
How to keep MK-677 sealed and once mixed, and when to throw a vial out. Storage only.
- Sealed powder: fridge at 2–8 °C, or freezer at −20 °C for long-term storage. Protect from light.
- Once mixed: refrigerate at 2–8 °C. Do not freeze. Discard after 60 days.
- Discard sooner if the solution turns cloudy, discoloured or shows particles.
| State | Where it is kept | How long |
|---|---|---|
| Sealed powder (unopened) | Fridge 2–8 °C, or freezer −20 °C; away from light | Long-term; keeps far longer than a mixed vial |
| Mixed | Fridge 2–8 °C; do not freeze | Discard after 60 days |
| Out of the fridge | Room temperature | Short spells only, measured in hours |
Sealed powder
Unopened, freeze-dried MK-677 is stored at 2–8 °C in the fridge, or at −20 °C in the freezer for long-term storage. Protect it from light. Sealed powder keeps far longer than a mixed vial and is more forgiving of a short spell out of the fridge.
Once mixed
The clock starts when you mix it. Keep the mixed vial in the fridge at 2–8 °C and do not freeze it. Discard it after 60 days.
That window is general guidance rather than a test on your specific vial. Purity, buffers and preservatives all change the answer, so the information supplied with your own vial takes precedence.
Out of the fridge
A short spell at room temperature, measured in hours, is generally tolerated. Heat is the single biggest cause of degradation, so the warmer it is the shorter the safe window, and days left warm is a different matter to a brief excursion. Keep it away from direct light too.
What breaks it down
Four things do the damage, in rough order: heat by a wide margin, then light, then repeated freezing and thawing, then agitation. Keep the vial in its box, away from light, and avoid shaking it.
When to throw it out
- 60 days after the date it was mixed.
- Any time the solution becomes cloudy or discoloured.
- Any time it contains particles.
Keep the mix date
Write the date you mixed it on the vial, or record it in a tracking app. Without that date there is no reliable way to know, which is the most common reason a vial gets used past its window or thrown away early.
Check any compound in the shelf life reference table → then save the vial in Peptide Wizard so it doesn’t expire half used. Pro warns you before a vial expires.
FAQ
How should sealed MK-677 be stored?
Unopened, freeze-dried MK-677 powder is stored at 2–8 °C in the fridge, or at −20 °C in the freezer for long-term storage, and protected from light.
How long does MK-677 last once mixed?
Once mixed, MK-677 is refrigerated at 2–8 °C and discarded after 60 days, or sooner if the solution turns cloudy, discoloured or shows particles. The information supplied with your own vial takes precedence.
Can mixed MK-677 be frozen?
No. The storage guidance for MK-677 says not to freeze it after mixing. Keep the mixed vial in the fridge at 2–8 °C.
How long can MK-677 be out of the fridge?
A short spell at room temperature, measured in hours, is generally tolerated, and sealed powder is more forgiving than a mixed vial. Heat is the single biggest cause of degradation, so the warmer it is the shorter the safe window.
When should a mixed MK-677 vial be thrown out?
After 60 days from the date it was mixed, or straight away if the solution becomes cloudy, discoloured or contains particles.
Educational only, not medical advice. This page covers storage and nothing else.