Modified GRF 1-29

Also called Mod GRF or CJC-1295 (no DAC). Stable GHRH fragment paired with a GHRP for optimal pulse.

Route: SubQShelf life once mixed: ~30 daysCategory: Growth Hormone

What Modified GRF 1-29 is

Modified GRF 1-29, also known as Mod GRF or CJC-1295 (without DAC), is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH), specifically a modified fragment corresponding to positions 1-29 of the natural GHRH molecule. It targets and binds to the GHRH receptors located on the somatotroph cells in the anterior pituitary gland. This binding stimulates the pituitary to release endogenous growth hormone (GH) in a pulsatile manner, mimicking the body's natural physiological rhythm. The amino acid modifications in its structure enhance its stability in the bloodstream, providing it with an approximate biological half-life of about 30 minutes, which is longer than natural GHRH but still relatively short.

When administered in research settings, potential effects related to growth hormone modulation are typically observed over several weeks to months of consistent use rather than immediately. Modified GRF 1-29 is frequently studied in combination with a Growth Hormone Releasing Peptide (GHRP) like Ipamorelin or GHRP-2, as this pairing is often noted to create a synergistic effect on the amplitude of growth hormone pulses. Research cycles typically range from several weeks to a few months, depending on the specific research parameters. Its relatively short half-life often necessitates multiple daily administrations to maintain consistent stimulation of GH release. This peptide is intended for research purposes only and is not for human medical use.

Commonly reported effects

Amplifies GHRP pulse
Improved recovery

Reported side effects & considerations

Flushing
Head rush

Storage & handling

LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.

AFTER RECONSTITUTION: refrigerate 2-8°C. Do NOT freeze. Discard after 30 days OR if the solution becomes cloudy, discolored, or contains particulates.

What people track

Because individual responses vary so much, the useful thing is your own record: what you logged and when, how much is left in the vial, and how your chosen metrics move over the weeks. Peptide Wizard keeps all of that in one place, alongside a 3D reference vial for Modified GRF 1-29.

FAQ

What is Modified GRF 1-29?

Also called Mod GRF or CJC-1295 (no DAC). Stable GHRH fragment paired with a GHRP for optimal pulse.

What do people commonly report with Modified GRF 1-29?

Commonly reported effects include amplifies ghrp pulse, improved recovery.

How should Modified GRF 1-29 be stored?

LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.

How do I keep track of Modified GRF 1-29 in my research log?

Peptide Wizard lets you record each entry, keep a vial ledger so you know what's left, and chart your own metrics over time. It is a logbook and reference only — it does not calculate or recommend doses.