HCG
Human Chorionic Gonadotropin. Mimics LH, stimulates testosterone and preserves fertility on TRT.
What HCG is
Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone that primarily functions by binding to and activating the luteinizing hormone/chorionic gonadotropin receptor (LHCG-R). This activation mimics the biological actions of endogenous luteinizing hormone (LH), leading to downstream signaling pathways. In males, HCG stimulates the Leydig cells within the testes, promoting the biosynthesis and secretion of testosterone and supporting spermatogenesis. The sustained presence of HCG helps maintain the size and function of the testes, preventing potential atrophy. Its half-life in the human body ranges from approximately 24 to 48 hours, allowing for less frequent administration compared to LH.
In research settings, HCG is often explored for its potential to support endocrine function, particularly in contexts where endogenous LH production may be suppressed, such as during exogenous testosterone administration. Effects on testosterone levels may be observed within days to a few weeks, with testicular volume and function preservation potentially manifesting over several weeks or months of consistent use. It is commonly investigated alongside testosterone replacement therapies to help mitigate testicular atrophy and maintain fertility parameters. Cycle lengths can vary depending on the research objective, often involving ongoing administration. It is crucial to note that HCG is a research peptide and is not intended for human consumption or therapeutic use; this information is for educational purposes only and does not constitute medical advice.
Commonly reported effects
- Testicular function preservation
- Fertility support
- Testosterone rise
Reported side effects & considerations
- Estrogen conversion
- Water retention
Storage & handling
LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.
AFTER RECONSTITUTION: refrigerate 2-8°C. Do NOT freeze. Discard after 30 days OR if the solution becomes cloudy, discolored, or contains particulates.
What people track
Because individual responses vary so much, the useful thing is your own record: what you logged and when, how much is left in the vial, and how your chosen metrics move over the weeks. Peptide Wizard keeps all of that in one place, alongside a 3D reference vial for HCG.
FAQ
What is HCG?
Human Chorionic Gonadotropin. Mimics LH, stimulates testosterone and preserves fertility on TRT.
What do people commonly report with HCG?
Commonly reported effects include testicular function preservation, fertility support, testosterone rise.
How should HCG be stored?
LYOPHILIZED (unopened): store at 2-8°C (fridge) or -20°C (freezer) long-term. Protect from light.
How do I keep track of HCG in my research log?
Peptide Wizard lets you record each entry, keep a vial ledger so you know what's left, and chart your own metrics over time. It is a logbook and reference only — it does not calculate or recommend doses.
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This page is educational. It does not contain dosing guidance and is not medical advice.